“Beware the variants!” scream the headlines all over the news. Now that the vaccine is available for SARS-CoV-2, we are pounded with endless daily fear-filled stories about how the variants of COVID are coming and will continue to put people in the hospitals and funeral homes. Are the variants that dangerous? Are there really wholesale mutations occurring in this virus that will make our natural immunity or vaccine immunity ineffective? According to my guest, Dr. Monica Gandhi, the answer is a simple no.